Wenger left the Gunners last year after a 22-year stay, but was heavily criticised for the latter part of his stay as he failed to regularly challenge for the Premier League and Champions League.
Pochettino has been linked with moves to Manchester United and Real Madrid, and although he sees his long-term future at Spurs, he would not want it to end like Wenger's reign across north London did.
"All that Arsene Wenger gave for Arsenal, to finish in the way it finished, yes, was a little bit unfair. And I think he deserves an amazing recognition about his work," Pochettino said.
"Only I hope, if I have the opportunity to talk with him is to ask if, 'Was it worth it to do?', I don't know what he would say, I would like to ask one day.
"I hope, or I wish to be here 20 years, and decide to leave or to finish my career here. But I don't know because I need to ask him one day if I have the possibility if he is so happy in the way that he finished.
"What I saw from my point of view, it was so unfair how the people treated him and talked. But we'll see."