Pac Man, 46, had shared the ring with Money Mayweather, 48, in May 2015 where he lost via unamimous decision, and Pacquiao has now revealed the pair could do battle once again.
Speaking at a press conference, he said: “Right now we have a lot of negotiations about my next fight; there's a possible rematch with Floyd Mayweather.
“There's a lot of ongoing negotiations right now, so it's hard to plan what fight I'm going to post. I'm waiting for the final negotiation.”
Pacquiao added he would “love” to face Mayweather again.
He continued: “I'd love to have another fight, a rematch with Floyd Mayweather. So I hope that in the negotiations, we can understand each other and we can negotiate well.”
Pacquiao and Mayweather had previously retired from the sport, though both have found their way back to the ring - with Pretty Boy competing in exhibition fights, and Pac Man returning to professoinal boxing in July to face Mario Barrios, 30.
This comes after Pacquiao announced he was “finalizing” a fight with Rolando Romero, 29.
He said of the bout: “We are negotating and finalizing.”
Although Pacquiao and Barrios had initially agreed to a rematch, Pac-Man’s advisor Sean Gibbons later argued a bout with Rolly would be a much better fight.
He told BoxingScene: “I don’t see why Barrios again. There’s Rolly Romero, [Gervonta] ‘Tank’ Davis. Why do it again? Mario Barrios doesn’t draw anything and brings nothing to the table but that belt.
“Rolly Romero would be an unbelievably fun fight and one hell of a promotion.”
Gibbons then added of a fight with Romero: “A Hall of Famer on my resume, who wouldn’t want that? “That’s the easiest way to get into the Hall of Fame, right?”
Pacquiao is said to want to fight Rolly in January or February 2026 after turning 47 in December. Pacquiao had initially retired from boxing in 2021 after losing to Yordenis Ugas, 39, though returned four years later to face Barrios.
In his match with Barrios, Pacquiao put on an excellent show, though was denied victory - with the bout ending in a majority draw and allowing El Azteca to retain his welterweight crown.