The 25-year-old, who is out of contract in July, was on loan at Bournemouth in the last campaign after a long battle with injuries but has kept fit and has been starring in Arsenal's Europa League side so far this season.
He has been restricted to just three substitute appearances in the Premier League, however, and has been overlooked by England boss Gareth Southgate.
Wenger insists he will take Wilshere's best interests into consideration when it comes to the decision over offering him a new deal or allowing him to leave in search of regular first-team action.
"I always considered his interest because for me he's an Arsenal player and has been since he was a kid," Wenger said. "He's a football man and I will always decide what is best for him, that is my first priority no matter what kind of decision I make. I have to consider the interests of Jack Wilshere and Arsenal Football Club together.
"If I think his best interest is to stay here then I will absolutely fight 100 per cent for him to stay here because he's a guy who is top quality and is back fit now."