An eventful week at Spurs saw Pochettino fired by Spurs chairman Daniel Levy, who wasted no time in drafting in a replacement with Mourinho in the hot seat just 12 hours later.
The Portuguese, back in the game after 11 months out, then led his new club to a 3-2 win at West Ham on Saturday lunchtime - their first Premier League away win since January 20.
Kane was a staunch supporter of Pochettino, crediting him with making him into one of the top strikers in the world, and he wanted the chance to say goodbye.
The England international says despite all the rumours, the departure of Pochettino still came as a shock to him, and he went to the Argentinean's house the day after to say his goodbyes.
Attention now turns to the future under the leadership of Mourinho, and Kane is excited by what it could hold for him and the club.
For all the brilliant work Pochettino did in making Spurs one of the best sides in England, his five-and-a-half-year stint ended without any silverware, despite two finals and three semi-finals.
Kane has never been quiet about his desire to win trophies at Spurs and he is hoping that Mourinho - a man with a plethora of titles to his name - can help him achieve his goals.
"The gaffer's won at every club he's gone to - there's no hiding away from that," Kane said.
"He wants to win. He's a proven winner. I've made it clear that I'm at the stage of my career where I want to win trophies.
"I've made it clear I want to win them here and it's a big year for us."
Winning the Champions League could be a tall order for Spurs this season, but there is no doubt they will be going all out for the FA Cup, while finishing in the top four is also a must.