The Chilean has featured in domestic knockout football this season and has played a key role as City have made it to this stage of the competition.
Elsewhere, midfielder Ilkay Gundogan and defenders Oleksandr Zinchenko and Danilo might also get more game time after playing in Saturday's FA Cup victory over Burnley.
The fitness of captain Vincent Kompany (calf) is unclear but left-back Benjamin Mendy (knee), midfielder Phil Foden (ankle) and striker Gabriel Jesus (knee) are definitely out.
Meanwhile, Gundogan has warned Bristol City that Manchester City are in no mood to ease up in the Carabao Cup.
The 27-year-old said: "They have beaten (Manchester) United, so of course it will be a tough challenge but we know we are the favorites.
"We play the first leg here at home, so, of course, we want to win that game. We want to win both games."
Provisional squad: Bravo, Ederson, Walker, Danilo, Kompany, Stones, Otamendi, Mangala, Delph, Zinchenko, Toure, Gundogan, Fernandinho, Diaz, Sterling, Sane, D Silva, B Silva, De Bruyne, Aguero.