The Scottish champions face their Glasgow rivals on Saturday (17.10.20) and Lennon feels the game could be decided by who adapts better to the unusual circumstances as no fans will be present due to crowd restrictions being in place due to the COVID-19 pandemic.
The Celtic boss said: "It is a huge ingredient that is going to be missing. The electricity, the atmosphere, the rawness, the noise – the colour.
"All that is going to be missing. You have to adapt to it as best you can.
"I think it is very difficult for this generation of players to go through what they are going through without supporters.
"We have adapted as well as anybody. Our focus has got to be on playing the game, obviously trying to win the game.
"That doesn't change. What they will miss is the noise and that edge these games bring. So we have to try to devise our own edge."
Celtic are a point behind Rangers, although they do have a game in hand, but Lennon feels it is far too early to draw any conclusions from the match and believes last season's games provide proof of the unpredictable nature of the derby.
He said: "It is way too early. We had this conversation after we won at Ibrox last year and after we lost at Celtic Park in December.
"It didn't pan out the way that people assumed it was going to or predicted."