It's said the decision has been made in the face of growing official concerns about the health impacts of vamping, with 42 deaths and more than 2,100 cases of lung injury in the US alone which can be linked to a respiratory illness connected to vaping.
In a statement to tech site Axios, Apple says it agrees with official warnings about the negative health impacts, and the possible problems presented by promoting e-cigarettes to young people.
A total of 181 apps will not be available on iPhones as a result of the move, with the company adding it took "great care" to make sure the app store was a place of trust.
Meanwhile, the tech giant also clarified that anyone who had already downloaded a vaping app onto their iPhone would be able to carry on using it, and could transfer it to any new Apple device.
Research by the US Centers for Disease Control and Prevention (CDC) suggested one ingredient - thickening agent vitamin E acetate - is to blame after looking into the causes of the respiratory disease.