Spurs fell to a 2-1 loss in the London derby against West Ham and have now lost five of their past six league games but Mourinho admits that he still has faith in his ability as a manager.
Asked if he doubts his methods, the Tottenham boss said: "No, not at all. Not at all. Zero. Sometimes results are a consequence of multiple situations in football.
"Mine, and my coaching staff's methods, are second to nobody in the world."
Mourinho also rejected claims that Tottenham are in crisis and believes that their second-half display showed that they are still fighting.
He told reporters: "I don't know what you mean by crisis.
"If crisis is frustration and sadness in the dressing room, I would say so, because nobody is happy, we all showed that in this game.
"When a team fights the way we did until the last second trying to get a different result, it is never a group in crisis. Groups are in crisis when you are not together in the search for better results than you have.
"So I wouldn't say crisis, I would say a really bad run of results. That is obvious. We are losing too many matches."
Tottenham are now nine points off the top four but Mourinho refused to give up on his team's hopes of qualifying for the Champions League via their league position.
He said: "It is still mathematically possible. When it is mathematically possible it is realistic, yes it's very hard, but mathematically it's possible."